Ash (Satoshi) and Misty (Kasumi)

Imma do parent bios too :3

Ash (original age 10)
At 16 years old, Ash took up Scott's offer from earlier to become a frontier brain. Prior to this, he began traveling with Gary and Misty. They went to every region together and and Ash felt complete which is why he decided to be become a frontier brain. Misty stuck around with Ash while he was. By the time Ash was 18 he had surpassed all of the champions of each region and was deemed Pokemon Master. He began traveling around with Misty again but as a Pokemon Master. When Ash became 20 he finally decided to marry Misty since she was being so supportive and they had been together for so long. 5 years later Ashley was born and 8 years later Micah was born.

Misty (original age 10)
For quite some time Misty was the gym leader of the Cerulean Gym but when Ash came back home from his most recent journey she decided to go with him and Gary. Her sisters took over the gym and she traveled with Ash. She also Stuck with Ash when he became a frontier brain. While she was she learned a lot from him since he was close to being a master so she later became a water Pokemon master. She and Ash married at 20